A large randomised placebo controlled trial among trauma patients with, or at risk of, significant haemorrhage, of the effects of antifibrinolytic treatment on death and transfusion requirement
ISRCTN86750102

THE USE OF TRANEXAMIC ACID

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Podcast ABC Television, Catalyst - Thin blood
Featuring the CRASH-2 trial and our Australian investigators
CRASH-2 Prognostic Model: Predicting early death in patients with traumatic bleeding: development and validation of prognostic model PowerPoint presentation of the trial results
TXA song by BDCC choir Ian Roberts presenting to the Massive Transfusion Consensus Conference in Canada in June 2011

CRASH-2 trial results: Effects of tranexamic acid on death, vascular occlusive
events, and blood transfusion in trauma patients with
significant haemorrhage (CRASH-2): a randomised,
placebo-controlled trial

pdf-version

 

  Comments from the collaborators CRASH-2 subgroup analysis: The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial; CRASH-2 Collaborators  

The promise of tranexamic acid, Dr Jerold H Levy, Emory University School of Medicine

Effect of consent rituals on mortality in emergency care research
Ian Roberts, David Prieto-Merino, Haleema Shakur, Iain Chalmers, Jon Nicholl

Interview of Utako Okamoto, the inventor of tranexamic acid

Cost-Effectiveness Analysis of Administering Tranexamic Acid to Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial. Carla Guerriero, John Cairns, Pablo Perel, Haleema Shakur, Ian Roberts

 

Wikipedia

    Cochrane Injuries Group  
   

Implementation of the CRASH-2 results into clinical practice
University of Leicester, Department of Cardiovascular Sciences FAQs

 
    BMC Emergency Medicine
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
 

RESULTS NEWS VIDEO

Last updated 08 May 2013